Functional assessment in advanced glaucoma

Glaucoma is a neurodegenerative disease of the optic nerve and the most common cause of irreversible blindness. Visual function of glaucoma patients can be tested reliably in early but not in advanced disease; visual function of patients reported to be blind by the current gold standard diagnostic technique (standard automated perimetry) ranges from barely light perception to useful vision for the majority of everyday tasks. The aim of the project is to enable quantification of visual function in those reported blind by standard automated perimetry.

Applied techniques involve psychophysics using modifications of existing perimetry techniques and novel approaches. This should result in a prototype novel device or a protocol describing the modified use of existing devices to quantify visual function in advanced glaucoma, on a single monotonic scale.

What can you expect?
You will gain extensive experience and expert insight into, among others, clinical ophthalmic assessment including perimetry and OCT, glaucoma care, basic and complex psychophysics, clinical electrophysiology, and assessment of daily-life functioning. You will be part of a vibrant, interdisciplinary research team and you will benefit from the wide academic exchange in national and international scientific networks.

The candidate will be located (1) in the Department of Ophthalmology of the UMCG of the University of Groningen, The Netherlands (PI: Jansonius) and (2) the Section for Clinical and Experimental Sensory Physiology of the Department of Ophthalmology of the Otto-von-Guericke University of Magdeburg, Germany (PI: Hoffmann), which both have a strong focus on glaucoma and the investigation of structure and function in eye diseases.

Who are we looking for?
We are looking for a highly motivated candidate with a strong interest in physiology, especially of the visual system, clinical care, physics, mathematics, and programming.


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